Decomposing contrasts

Function for decomposing one or several observed contrasts (comparisons between conditions).

decomposeVar()

Decompose input contrasts to decoded and residual fractions

Identifying similar contrasts

Search a large human or mouse database (derived from ARCHS4) for contrasts similar to your own one(s).

loadContrastDatabase()

Load contrast database

queryWithContrasts()

Query the contrast database with a set of contrasts

plotQueryResultsManh()

Visualize query results as a composite manhattan/density plot.

plotQueryResultsViolin()

Visualize query results as violin plots

Misc functions

testOrthosEnv()

Test conda environment

General package information

orthos orthos-package

orthos - variance decomposition using conditional variational auto-encoders